职称:副教授
学科专业:生物化学与分子生物学
研究方向:医学分子生物学与干细胞转化医学
个人简介:科研方向专注于干细胞生物学研究,2011-2012年在美国康乃涅克大学遗传发育学实验室做访问学者,主要从事分子生物学技术调控干细胞定向诱导分化的研究。近年来结合临床运动系统的医学难题,专注干细胞临床转化机制的研究,尤其是椎间盘髓核干细胞的生物学特性及增殖、分化的分子机理。
2003/09 – 2006/06, 中山大学,干细胞与组织工程研究中心,博士
1999/09 – 2002/06,皖南医学院,基础医学院病理生理学系,硕士
1991/09 – 1996/06,皖南医学院,临床医学系,学士
2011/04- 2012/05 美国Connecticut 州立大学,医学中心遗传发育学系,访问学者&博士后
2008/10 - 至今, 暨南大学医学院 生物化学系, 副教授
2006/09 -2008/09 暨南大学医学院 生物化学系, 讲师
1.Hao Wu, Xiaoli Zeng, Yupan Shang,Lek Hang Cheang, Jiaqing Zhang.Effect of Conditioned Medium from Human Umbilical Cord-Derived Mesenchymal Stromal Cells on Rejuvenation of Nucleus Pulposus Derived stem/Progenitor Cells from Degenerated Intervertebral Disc. International Journal of Stem Cells 2020. https://doi.org/10.15283/ijsc20027 (通讯作者)
2.Hao Wu, Xiaoli Zeng, Yupan Shang,Lek Hang Cheang, Jiaqing zhang.Regenerative potential of human nucleus pulposus resident stem/progenitor cells declines with ageing and intervertebral disc degeneration. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 2018. DOI: 10.3892/ijmm.2018.3766 (通讯作者)
3.Hao Wu, Xiaoli Zeng, Yupan Shang,Lek Hang Cheang, Jiaqing Zhang. Comparison of nucleus pulposus stem/progenitor cells isolated from degenerated intervertebral discs with umbilical cord derived mesenchymal stem cells. Experimental Cell Research 2017(361):324-332(A1, II区,IF 3.6)(通讯作者)
4.Hao Wu, Yupan Shang, Jiaqing Zhang, Lek Hang Cheang,Xiaoli Zeng and Mei Tu The effects of liquid crystal-based composite substrates on cell functional responses of human umbilical cord-derived mesenchymal stem cells by mechano-regulatory process Journal of Biomaterials Applications 2017, Vol. 32(4) 492–503 (A1, II区,IF 3.2)(通讯作者)
5.尚玉攀, 吴 昊, 曾晓丽, 郑力恒, 余 俊, 肖黔龙, 屠 美, 张嘉晴, 从脊柱内镜手术摘除组织中分离髓核间充质干细胞及其生物学特征鉴定中国病理生理杂志 2017, 33 (6): (通讯作者)
6.Zhang JQ, Yu WH, Zhang XM, Peng YW, Li WH, Chen R, Yu XB, Li SH, Xiang P. Establishment and characteristics of hybrid embryonic stem cell lines from blastocysts of the(C57BL/6J× 129/J)F1 mouse(英文). 中国病理生理杂志 Chinese Journal of pathophysiology 2006, 22(1):7-11(第一作者)
7.Li Kairong, Zhang Jiaqing, Li James YH. Gbx2 plays an essential but transient role in the formation of thalamic nuclei. PLoS One. 7(10) 2012;
8.Yang Chen, Lei Wang, Hao Huang, Ruizhe Tan, Jupeng Zhao, Shenyu Yang, Rong Zeng, Hao Wu,Jiaqing Zhang, Bin Yu, Mei Tu. Mechano-regulatory Cellular Behaviors of NIH/3T3 in Response to the Storage modulus of Liquid Crystalline Substrates. Journal of the Mechanical Behavior of Biomedical Materials , 2016.4, 57: 42~54
9.Tan Wen-cheng, Zha Zhen-gang*.,Zhang Jia-qing,Zheng Li-heng,Liang Yao-zhong,Xia Ji-sheng,Huang Xin-pei1,Wu Hao,Lin Hong-sheng Animal-origin osteochondral scaffold combined with bone marrow mesenchymal stem cells/chondrocytes for repair of composite osteochondral defects in rabbit knee joints Journal of Clinical Rehabilitative Tissue Engineering Research, 89(12):209-214. 2011
10.Zhang HT, Zha ZG*, Cao JH, Liang ZJ, Wu H, He MT, Yao P, Zhang JQ. Apigenin accelerates lipopolysaccharide induced apoptosis in mesenchymal stem cells through suppressing vitamin D receptor expression. Chin Med J (Engl).124(21):3537-45. 2011
11.郭燕珊; 吴昊; 郑力恒; 尚玉攀; 屠美; 张嘉晴(通讯作者)聚合物/液晶细胞模型的构建及其表面弹性对大鼠骨髓干细胞黏附的影响,中国病理生理杂志 2015,31 (6):1064-1069.
12.李佳成; 郭燕珊; 屠美; 吴昊; 郑力恒; 张嘉晴(通讯作者);胚胎干细胞条件培养基对人脂肪干细胞增殖及分化能力的影响 中山大学学报(医学科学版)2014, 35 (2):169-176.
13.Zhang JQ, Yu XB, Ma BF, Yu WH, Zhang AX, Huang G, Mao FF, Zhang XM, Wang ZC,Li SN, Lahn BT, Xiang AP*. Neural differentiation of embryonic stem cells induced by conditioned medium from neural stem cell. Neuroreport. 17;17(10):981-6. 2006
14.Zhang AX, Yu WH, Ma BF, Yu XB, Mao FF, Liu W, Zhang JQ, Zhang XM, Li SN, Li MT, Lahn BT, Xiang AP*. Proteomic identification of differently expressed proteins responsible for osteoblast differentiation from human mesenchymal stem cells. Mol Cell Biochem. 304(1-2):167-79. 2007
15.Ma BF, Liu XM, Xie XM, Zhang AX, Zhang JQ, Yu WH, Zhang XM, Li SN, Lahn BT, Xiang AP*.. Slower cycling of nestin-positive cells in neurosphere culture. Neuroreport. 17(4):377-81. 2006.
2015年 获暨南大学本科课程全英语教学竞赛校长奖二等奖
2015年 获暨南大学医学院本科课程全英语教学竞赛一等奖
2008年获暨南大学医学院本科教学竞赛三等奖
中国生物化学与分子生物学学会会员