个人简介

职称：副教授

学科专业：病原生物学

研究方向：研究领域集中在秀丽线虫发育、遗传、跨代遗传，衰老及抗衰老机制研究

电子邮箱：wanqinli@ hotmail.com

个人简介：

副教授，硕士生导师，研究领域集中在秀丽线虫发育、遗传、跨代遗传，衰老及抗衰老机制研究。目前研究成果以第一作者或通讯作者在Nature Communications，Science Advances，ACS Sustainable Chemistry and Engineering等杂志上发表论文10余篇。主持包括国家自然科学基金青年项目、广东省基础与应用基础研究基金青年项目及中国博士后基金等。

学习经历

(1) 2013-09 至 2017-07, 中国科学院昆明植物研究所, 生物化学与分子生物学, 博士

(2) 2010-09 至 2013-07, 中国科学院昆明植物研究所, 生物化学与分子生物学, 硕士

(3) 2006-09 至 2010-07, 北京中医药大学, 中药制药, 学士

工作经历

(1) 2021-10 至 今, 暨南大学，基础医学与公共卫生学院,，副教授

(2) 2020-11 至 2021-10, 暨南大学， 基础医学与公共卫生学院， 讲师

(3) 2017-11 至 2020-11，暨南大学博士后

主要论文

1） Luo Zhenhuan, Dai Wenyu, Wang Chongyang, Ye Qunshan, Zhou Qinghua, Wan Qin-Li *, Gene activation in Caenorhabditis elegans using the Campylobacter jejuni CRISPR-Cas9 feeding system. G3 Genes| Genomes| Genetics, 2022.

2） Wan Qin-Li #, Meng Xiao #, Wang Chongyang, Dai Wenyu, Luo Zhenhuan, Yin Zhinan, Ju Zhenyu, Fu Xiaodie, Yang Jing, Ye Qunshan, Zhang Zhanhui, Zhou Qinghua *, Histone H3K4me3 modification is a transgenerational epigenetic signal for lipid metabolism in Caenorhabditis elegans. Nature Communications, 2022, 13(1), 768.

3） Wan Qin-Li, Meng Xiao, Dai Wenyu, Luo Zhenhuan, Wang Chongyang, Fu Xiaodie, Yang Jing, Ye Qunshan, Zhou Qinghua *, N6-methyldeoxyadenine and histone methylation mediate transgenerational survival advantages induced by hormetic heat stress. Science Advances, 2021, 7(1), eabc3026.

4） Wan Qin-Li, Shi Xiaohuo, Liu Jiangxin, Ding Ai-Jun, Pu Yuan-Zhu, Li Zhigang, Wu Gui-Sheng *, and Luo Huai-Rong *, Metabolomic signature associated with reproduction-regulated aging in Caenorhabditis elegans. Aging (Albany NY), 2017. 9(2): p. 447-474. 

5） Wan Qin-Li, Meng Xiao, Fu Xiaodie, Chen Bohui, Yang Jing, Yang Hengwen *, Zhou Qinghua *, Intermediate metabolites of the pyrimidine metabolism pathway extend the lifespan of C. elegans through regulating reproductive signals. Aging (Albany NY), 2019, 11(12): p. 3993-4010.

6） Zhao Xiujun #, Wan Qin-Li #, Fu Xiaodie, Meng Xiao, Ou Xianfeng, Zhong Ruowei, Zhou Qinghua *, Liu Mingxian *, Toxicity evaluation of one-dimensional Nanoparticles using Caenorhabditis elegans: a comparative study of Halloysite Nanotubes and Chitin Nanocrystals. ACS Sustainable Chemistry and Engineering. 2019, 7(23): p. 18965-18975.

7） Wan Qin-Li, Fu Xiaodie, Meng Xiao, Luo Zhenhuan, Dai Wenyu, Yang Jing, Wang Chongyang, Wang Hao *, Zhou Qinghua *, Hypotaurine promotes longevity and stress tolerance via the stress response factors DAF-16/FOXO and SKN-1/NRF2 in Caenorhabditis elegans. Food and Function. 2020, 11(1): p. 347-357. 

8） Wan Qin-Li #, Fu Xiaodie #, Dai Wenyu, Yang Jing, Luo Zhenhuan, Meng Xiao, Liu Xiao, Zhong Ruowei, Yang Hengwen *, Zhou Qinghua *, Uric acid induces stress resistance and extends the life span through activating the stress response factor DAF-16/FOXO and SKN-1/NRF2. Aging (Albany NY). 2020, 12(3): p. 2840-2856

9） Wan Qin-Li, Yang Zhong-Lin, Zhou Xiao-Gang, Ding Ai-Jun, Pu Yang-Zhu, Luo Huai-Rong, Wu Gui-Sheng *, The Effects of Age and Reproduction on the Lipidome of Caenorhabditis elegans. Oxidative medicine and cellular longevity, 2019, 2019:5768953.

10） Wan Qin-Li, Zheng Shan-Qing, Wu Gui-Sheng, Luo Huai-Rong *, Aspirin extends the lifespan of Caenorhabditis elegans via AMPK and DAF-16/FOXO in dietary restriction pathway. Exp Gerontol, 2013. 48(5): p. 499-506.

11） Jia Wenjuan #, Wang Chongyang #, Zheng Jingming, Li Yimin, Yang Caixian, Wan Qin-Li *, Shen Jie *. Pioglitazone Hydrochloride Extends the Lifespan of Caenorhabditis elegans by Activating DAF-16/FOXO-and SKN-1/NRF2-Related Signaling Pathways[J]. Oxidative Medicine and Cellular Longevity, 2022, 2022

学术著作

获奖及荣誉 

学术兼职