免疫学 研究员
职称：研究员
学科专业：免疫学
研究方向：肿瘤分子机制及肿瘤免疫
行政职务：无
电子邮箱：seta1988@jnu.edu.cn
个人介绍：林雪嘉博士2014年毕业于中山大学生命科学学院，获博士学位，随后作为高层次人才被暨南大学引进入校。现任研究员，博士研究生导师。目前已获得“广东省特支计划科技创新青年拔尖人才”“广东省百名博士博士后创新人物”“广州市珠江科技新星”等学术荣誉；在Nature、Lancet Oncology、Molecular Cancer等国际知名刊物发表研究论文多篇；主持国家自然科学基金面上基金、青年基金项目等国家级及省部级项目共8项；作为主要发明人获批中国发明专利6项。
2009.09-2014.12 中山大学，生物化学与分子生物学，庄诗美教授实验室，博士
2005.09-2009.07 华南师范大学，生物科学，学士
2026.01至今，暨南大学，基础医学与公共卫生学院，生物医学转化研究院，研究员
2015.07-2025.12暨南大学，生物医学转化研究院，副研究员
2016.04-2018.02 美国加州大学圣地亚哥分校，药理学院，Michael Karin院士实验室，访问学者
1. Yu Huang#, Ying Xie#, Yuqing Zhang, et al. Single-cell transcriptome reveals the reprogramming of immune microenvironment during the transition from MASH to HCC. Molecular Cancer 2025. 24(1):177. (Correspondence, IF:33.9)
2. Ying Xie#, Yu Huang#, Zhi-Yong Li#, et al. Interleukin-21 receptor signaling promotes metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma by inducing immunosuppressive IgA+ B cells. Molecular Cancer 2024.23(1):95. (Correspondence, IF:33.9)
3. Chaohu Pan, Hongzhen Tang, Wei Wang, et al. An enhanced genetic mutation-based model for predicting the efficacy of immune checkpoint inhibitors in patients with melanoma. Frontiers in Oncology 2023.12:1077477. (Correspondence, IF:3.3)
4. Zhi-Yong Li#, Ying Xie#, Mingxia Deng#, et al. c-Myc-activated intronic miR-210 and lncRNA MIR210HG synergistically promote the metastasis of gastric cancer. Cancer Letters 2022.526:322-334. (Correspondence, IF:10.1)
5. Wan He#, Gengpeng Lin#, Chaohu Pan#, et al. The Identification of Two RNA Modification Patterns and Tumor Microenvironment Infiltration Characterization of Lung Adenocarcinoma. Frontiers in Genetics 2022.13:761681. (Correspondence, IF:2.8)
6. Xue-Jia Lin#, Jian-Hong Fang#, Xiao-Jing Yang, et al. Hepatocellular carcinoma cell-secreted exosomal microRNA-210 promotes angiogenesis In Vitro and In Vivo. Molecular Therapy Nucleic Acids 2018.11:243~252. (IF:6.1)
7. Shabnam Shalapour, Xue-Jia Lin, Ingmar N. Bastian, et al. Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature 2017.551(7680):340~345. (IF: 48.5)
8. Xue-Jia Lin#, Yutian Chong#, Zhi-Wei Guo#, et al. A serum microRNA classifier for early detection of hepatocellular carcinoma: a multicentre, retrospective, longitudinal biomarker identification study with a nested case-control study. Lancet Oncology 2015.16(7):804~815. (IF: 35.9)
9. Jing-Jing Liu#, Xue-Jia Lin#, Xiao-Jing Yang, et al. A novel AP-1/miR-101 regulatory feedback loop and its implication in themigration and invasion of hepatoma cells. Nucleic Acids Research 2014. 42(19):12041~12051. (Co-first, IF: 13.1)
2019年度广东省特支计划科技创新青年拔尖人才
2020年度广东省百名博士博士后创新人物
2019年度广州市珠江新星
