微生物与免疫学系 副教授
职称:副教授(绿色通道聘)
学科专业:免疫学
研究方向:细胞外囊泡、老年医学
行政职务:无
电子邮箱:lishuyu@jnu.edu.cn
个人介绍:利时雨,博士,暨南大学基础医学与公共卫生学院微生物与免疫学系副教授(绿色通道聘)。主要从事细胞外囊泡和线粒体靶点在老年医学领域的治疗应用,先后在Signal Transduction and Targeted Therapy、Advanced Science、Acta Biomaterialia等期刊发表SCI论文24篇。主持国自然青年基金、中国博士后科学基金、广东省区域联合基金青年项目、广东省自然科学基金面上项目、暨南大学科协青年科技人才托举工程项目。参与国家重点研发计划、国自然面上项目、广东省区域联合基金重点项目。
2018-09至2021-06,南方医科大学,人体解剖与组织胚胎学专业,博士
2015-09至2018-06,南方医科大学,生物化学与分子生物学专业,硕士
2009-09至2014-06,广州医科大学,临床医学专业,本科
2024-06至今,暨南大学基础医学与公共卫生学院,副教授
2021-07至2024-05,南方医科大学第三附属医院,博士后
[1] Li S#, Liu S#, Jiang Z#, Feng L, Gao Y, Chen Y, Xu A, Huang W*, Zhang N*, Sun H*. Study on the promotion of lymphocytes in patients with COVID-19 by broad-spectrum chemokine receptor inhibitor vMIP-II and its Mechanism of signal transmission in vitro. Signal Transduct Target Ther. 2021 Mar 2;6(1):104. (IF:38.120,1区Top)
[2] Li S#, Zheng W#, Deng W#, Li Z, Yang J, Zhang H, Dai Z, Su W, Yan Z, Xue W, Yun X, Mi S, Shen J, Luo X, Wang L*, Wu Y*, Huang W*. Logic-Based Strategy for Spatiotemporal Release of Dual Extracellular Vesicles in Osteoarthritis Treatment. Adv Sci (Weinh). 2024 Jul;11(26):e2403227. (IF:14.3,1区Top)
[3] Yang Y#, Zheng W#, Tan W#, Wu X#, Dai Z, Li Z, Yan Z, Ji Y, Wang Y, Su W, Zhong S, Li Y, Sun Y*, Li S*, Huang W*. Injectable MMP1-sensitive microspheres with spatiotemporally controlled exosome release promote neovascularized bone healing. Acta Biomater. 2023 Feb;157:321-336. (IF:9.4,1区Top)
[4] Yan Z#, Yang J#, Zhang H#, Li Z, Zheng W, Li S*, Huang W*. The effect of depression status on osteoarthritis: A powerful two-step Mendelian randomization study. J Affect Disord. 2024 Nov 1;364:49-56. (IF:4.9,二区Top)
[5] Wang Y#, Li S#, Liu M, Wang J, Fei Z, Wang F, Jiang Z, Huang W*, Sun H*. Rhodosporidium toruloides sir2-like genes remodelled the mitochondrial network to improve the phenotypes of ageing cells. Free Radic Biol Med. 2019 Apr;134:64-75. (IF:6.170,二区Top)
[6] Zhang L#, Dai Z#, Shi S#, Yan Z, Yang J, Xue W, He Y, Mi S, Cheng C, Wang L, Li N, Tan W, Jiang Z*, Sun H*, Li S*. SIRT3 and SIRT4 double-genes remodeled the mitochondrial network to induce hepatocellular carcinoma cell line differentiation and suppress malignant phenotypes. Biochem Pharmacol. 2024 May;223:116168. (IF:5.3,二区)
[7] Deng J#, Zhong Z#, Geng C#, Dai Z, Zheng W, Li Z, Yan Z, Yang J, Deng W, Tan W*, Sun H*, Li S*. Herpes Simplex Type 1 UL43 Multiple Membrane-Spanning Protein Increases Energy Metabolism in Host Cells through Interacting with ARL2. Cells. 2022 Nov 14;11(22):3594. (IF:6.0,二区)
[8] Li Z#, Zhang H, Zheng W, Yan Z, Yang J, Li S*, Huang W*. Esaxerenone Protects against Diabetic Cardiomyopathy via Inhibition of the Chemokine and PI3K-Akt Signaling Pathway. Biomedicines. 2023 Dec 15;11(12):3319. (IF:3.9,三区)
[9] Dai Z#, Li Z#, Zheng W#, Yan Z, Zhang L, Yang J, Xiao J, Sun H*, Li S*, Huang W*. Gallic Acid Ameliorates the Inflammatory State of Periodontal Ligament Stem Cells and Promotes Pro-Osteodifferentiation Capabilities of Inflammatory Stem Cell-Derived Exosomes. Life (Basel). 2022 Sep 6;12(9):1392. (IF:3.2,三区)
[10] Li S#, Liu S#, Dai Z, Zhang Q, Xu Y, Chen Y, Jiang Z*, Huang W*, Sun H*. The UL16 protein of HSV-1 promotes the metabolism of cell mitochondria by binding to ANT2 protein. Sci Rep. 2021 Jul 7;11(1):14001. (IF:4.997,三区)
第四届广东医学科技奖-医学科普奖
广东省生物医学工程学会植入器械与先进制造分会委员
广东省科普作家协会委员
广东省精准医学应用学会数字医学分会会员
广东省增材制造研究与应用协会会员
Regenerative Biomaterials、International Journal of Bioprinting、Cancer Cell International审稿人